Resistance to something such as a change or a new idea is a refusal to accept it.

Resistance to an attack consists of fighting back against the people who have attacked you.

The resistance of your body to germs or diseases is its power to remain unharmed or unaffected by them.

Wind or air resistance is a force which slows down a moving object or vehicle.

In electrical engineering or physics, resistance is the ability of a substance or an electrical circuit to stop the flow of an electrical current through it.

In a country which is occupied by the army of another country, or which has a very harsh and strict government, the resistance is an organized group of people who are involved in illegal activities against the people in power.

If you take the line of least resistance in a situation, you do what is easiest, even though you think that it may not be the right thing to do. In American English, you usually talk about the path of least resistance .